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Vaccine Prep (ATA)

Personalized cancer vaccines are a groundbreaking approach to treatment in cancer care. Our Vaccine Prep (ATA) therapy stands at the forefront of this movement, offering patients a truly individualized cancer vaccine therapy that harnesses their body's own immune system to fight cancer. This innovative personal cancer vaccine is a valuable advancement in autologous personalized cancer therapy, providing hope for patients seeking targeted, effective treatment options.

What is Vaccine Prep Therapy?

Vaccine Prep (ATA) is an advanced form of vaccine therapy for cancer that creates a personalized treatment specifically tailored to each patient's unique cancer profile. This exciting approach represents the next generation of cancer vaccine technology, moving beyond traditional one-size-fits-all treatments to deliver truly individualized care.

The foundation of our Vaccine prep therapy lies in the sophisticated analysis of circulating tumor cells (CTCs) found in a patient's blood. CTCs are cells that have broken off of the primary tumor and entered the bloodstream. What makes these cells particularly valuable for personalized cancer vaccines is their rich content of tumor-associated antigens (TAAs).

Tumor cells express an extensive array of both characterized and uncharacterized tumor-associated antigens. These antigens contain epitopes that can stimulate both CD8+ cytotoxic T cells (CTLs) and CD4+ T helper cells. This dual presentation of MHC Class I and II restricted antigens is crucial for generating a robust, comprehensive anti-tumor immune response and establishing long-term CD8+ T cell memory through CD4+ T helper cell activation.
What sets Vaccine Prep (ATA) apart as a personal cancer vaccine is its use of antigens derived directly from each patient's own tumor cells. Since tumor cells from each patient potentially carry unique gene mutations encoding for specific TAAs, this approach ensures that the vaccine is perfectly matched to the individual's cancer biology. This personalization is essential for stimulating effective and long-lasting anti-tumor responses that are specifically targeted to the patient's unique cancer profile.
Vaccine Prep (ATA) - T Cell 1 (1)

How does Vaccine Prep (ATA) work?

Understanding the mechanism behind this cancer vaccine therapy helps illustrate why it represents such a significant advancement in personalized cancer therapy.

The process begins with a simple blood draw from the patient. From this blood sample, our advanced laboratory techniques isolate circulating tumor cells using sophisticated flow cytometry technology. This process achieves a robust sample of cells, providing an excellent foundation for creating the personalized cancer vaccine.
Every cancer is unique, even cancers of the same type occurring in the same organ. Each patient’s tumor cells carry specific genetic mutations and express particular proteins that make them distinct from both normal cells and other patients' cancer cells. These unique characteristics, called tumor-associated antigens, serve as identifying markers that the immune system can learn to recognize and target.

The beauty of using one’s own tumor cells for vaccine therapy for cancer lies in this specificity. Rather than using generic antigens that may or may not be present in a patient’s particular cancer, Vaccine Prep (ATA) ensures that the immune system is trained to recognize the exact molecular signatures present in the patient’s specific tumor.
The isolated tumor cells undergo a carefully controlled process to create necrotic whole tumor cell lysate. This established method, already used in clinical trials, involves making the tumor cells necrotic through specialized techniques. The resulting material contains a comprehensive mixture of cellular components, including fragments of destroyed cellular membranes, intracellular organelles such as mitochondria, and cellular RNA and DNA.

This approach ensures that the cancer vaccine contains the complete spectrum of potential antigens present in the patient's tumor, maximizing the chance of stimulating a broad and effective immune response.
While it might seem counterintuitive, necrotic tumor cells are actually superior to live tumor cells for personalized cancer vaccines. Live tumor cells are poorly immunogenic and can secrete soluble factors which can actually suppress the differentiation and maturation of dendritic cells – the very cells needed to present antigens to the immune system.

In contrast, necrotic tumor cells have been shown to induce partial maturation in dendritic cells without requiring additional maturation stimuli. This is likely due to the abundance of heat shock proteins released from dead cells during the necrosis process, which act as natural danger signals to alert the immune system.
Once administered, the personal cancer vaccine works by presenting the tumor antigens to the patient's immune system in a way that promotes recognition and memory. Dendritic cells take up these antigens and present them to T cells, effectively "training" the immune system to recognize and attack cancer cells displaying these same antigens.

The parallel presentation of both MHC Class I and II restricted antigens helps generate a stronger overall anti-tumor response. CD8+ cytotoxic T cells directly attack cancer cells, while CD4+ T helper cells coordinate the immune response and help establish long-term immunological memory.

Who is Vaccine Prep (ATA) for?

Understanding who can benefit from this autologous vaccine therapy for cancer is crucial for patients and healthcare practitioners considering this treatment option.

Cancers Vaccine Prep (ATA) Can Treat

Vaccine Prep (ATA) has shown effectiveness in treating various types of solid tumors. This includes cancers such as:

The personalized cancer vaccine approach is particularly well-suited to solid tumors because these cancers shed circulating tumor cells into the bloodstream, providing the necessary starting material for vaccine creation.

Cancers Vaccine Prep (ATA) Cannot Treat

Certain types of cancers are not suitable for this cancer vaccine therapy, including:

  • Hematologic cancers (blood cancers such as leukemia, lymphoma, and multiple myeloma)
  • CNS cancers (central nervous system tumors)
  • Testicular cancers
  • Compartmentalized cancers that remain isolated within specific organs, such as brain tumors

These limitations are primarily due to the biology of these cancer types and their tendency not to shed circulating tumor cells in sufficient quantities for vaccine preparation.

Contact Us to Learn More

At what cancer stage should a patient consider Vaccine Prep Therapy?

This personalized cancer therapy works best under specific conditions, particularly when the patient has an intact, functioning immune system. Patients should consider Vaccine Prep (ATA) when they are:

  • In the early stages of the disease process
  • Treatment-naive (have not undergone chemotherapy or radiation)
  • Not on immune suppression therapies
  • Have a robust immune system capable of mounting an effective response

Early-stage patients typically have the best outcomes because their immune systems have not been compromised by aggressive treatments, and the cancer burden is more manageable.

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Therapy Details

Understanding the practical aspects of vaccine therapy for cancer helps patients prepare for treatment and set appropriate expectations.

Yes, Vaccine Prep (ATA) is considered safe. As a personalized cancer vaccine that uses antigens derived from the patient's own circulating tumor cells, it comes with all the safety advantages inherent in personalized therapy. The treatment uses the patient's own biological material, significantly reducing the risk of adverse reactions.

The safety profile is supported by extensive clinical experience, with over 1,150 clinical trials conducted on similar approaches to cancer vaccine therapy. This extensive research base provides confidence in the safety and tolerability of the treatment approach.

The personalized cancer therapy follows a structured administration schedule designed to maximize immune system activation:

Total duration: Nine weeks of active treatment

Administration frequency: Doses on day 0, day 8, day 15, day 39, day 47, and day 55

Follow-up testing: Oncotrace and Immune Frame tests conducted after completion of the nine-week treatment cycle, on day 72

This schedule is carefully designed to allow for proper immune system priming and response development while monitoring treatment effectiveness.

As part of the treatment process, specific tests are required to monitor progress and ensure safety:

Oncotrace: Monitors circulating tumor cell levels and treatment response

Immune Frame: Assesses immune system function and response to the vaccine

These tests provide valuable insights into how well the personal cancer vaccine is working and whether any adjustments to the treatment plan are needed.

While Vaccine Prep (ATA) is generally well-tolerated, some patients may experience mild side effects:

Common reactions include:

  • Flu-like symptoms
  • Fatigue
  • Low-grade fever
  • Injection site reactions (such as mild skin rash)
  • Urticaria (hives) in some cases

Important safety note: There have been no reported severe, life-threatening anaphylactic reactions from this procedure to date. However, as with any medical treatment, there is no absolute guarantee that severe reactions will not occur, though they would be extremely rare.

Most side effects are mild and typically resolve within a few days of administration. These reactions often indicate that the immune system is responding appropriately to the cancer vaccine.

Several factors may prevent a patient from being a suitable candidate for this cancer vaccine:

  • Advanced stage disease where the immune system may be too compromised
  • Current or recent chemotherapy or radiation therapy
  • Immune suppressant medications
  • Recent blood transfusions
  • Cachexia (severe weight loss and muscle wasting)
  • Pregnancy or breastfeeding
  • Active infections or high inflammation levels
  • Children under 18 years of age
  • Active autoimmune disease
  • Patients with radioactive seeds due to prolonged radiation exposure
  • Patients currently receiving Gamma Delta T Cell Therapy (GDTC) due to potential interactions

The restriction for children exists because Vaccine Prep has not been evaluated in pediatric populations. Children's immune systems are still developing self-tolerance, and they have active thymus glands with immune systems under development, making the effects of this therapy unpredictable.

Patients should consult with their RGCC Practitioner about other potential contraindications.

Clinical Outcomes

The effectiveness of personalized cancer vaccines like Vaccine Prep (ATA) continues to be evaluated through ongoing clinical research and patient monitoring. The personalized nature of this cancer vaccine therapy means that outcomes can vary significantly between patients, depending on factors such as:

  • Cancer type and stage at treatment initiation
  • Individual immune system capacity
  • Overall health status
  • Adherence to treatment protocols

The wealth of clinical trial data supporting vaccine therapy for cancer approaches provides a strong foundation for continued development and refinement of these treatments. As more patients receive Vaccine Prep (ATA), the understanding of optimal patient selection and treatment protocols continues to evolve.

Contact Us to Learn More

Why Choose Vaccine Prep (ATA)?

Several factors make Vaccine Prep (ATA) an attractive option for eligible patients seeking personalized cancer therapy:

Personalization: Unlike traditional treatments that take a one-size-fits-all approach, this personal cancer vaccine is created specifically for each patient's unique cancer biology.

Safety Profile: The use of the patient's own cellular material minimizes the risk of adverse reactions while maximizing compatibility.

Immune System Activation: Rather than suppressing the immune system like many conventional treatments, Vaccine Prep (ATA) works to strengthen and focus the body's natural cancer-fighting capabilities.

Comprehensive Antigen Presentation: The use of whole tumor cell lysate ensures exposure to the complete spectrum of tumor antigens, potentially providing broader protection against cancer recurrence.

Integration with Other Treatments: This cancer vaccine therapy can potentially be integrated with other treatment modalities as part of a comprehensive cancer care plan.

Scientific Foundation: Backed by extensive research and clinical trial experience in vaccine therapy for cancer, providing confidence in the approach.

couple hiking

Ready to Explore Personalized Cancer Care?

Vaccine Prep (ATA) is a significant advancement in personalized cancer vaccines, offering hope for patients seeking targeted, effective treatment options. This innovative cancer vaccine therapy harnesses the power of each patient's unique tumor biology to create a truly personalized treatment approach.

RGCC certified practitioners have undergone key training in RGCC's testing methodologies and treatment protocols in order to provide expert guidance on this personalized cancer therapy.

The journey toward personalized cancer care begins with understanding options. Vaccine Prep (ATA) offers a promising path forward for eligible patients, combining cutting-edge science with the precision of personalized medicine to fight cancer on your terms.

To learn more about Vaccine Prep (ATA) and other personalized cancer vaccines, contact us today.

Together, we can explore how this innovative cancer vaccine might help empower the journey toward better health and recovery.

Get in Touch
The information provided is for general educational purposes and should not replace professional medical advice.

Videos

Explore our curated collection of videos, providing an in-depth look at our innovative solutions and groundbreaking research.

  • Dr Clayton Bell video cover
    Dr. Clayton Bell, MD | Gathering 2023 Interview

    In this insightful interview from the 2023 RGCC Gathering, Dr. Clayton Bell shares his journey of integrating RGCC technologies into his practice in the U.S.

    With a background in Functional, Environmental, and Integrative Medicine, Dr. Bell reveals how he uses RGCC’s cutting-edge cancer diagnostics and therapies to support his patients’ healing. Watch the full video to learn more.

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    Helena Pohlmann | Gathering 2023 Interview

    Helena Pöhlmann who specializes in holistic medicine shares how she utilizes RGCC products in her clinic to best support her patients. Watch the video to learn about her experience at the 2023 RGCC Gathering in Switzerland.

    Jenny Hrbacek, RN | About RGCC Testing

    Cancer survivor and RGCC Practitioner, Jenny Hrbaceck, discusses RGCC testing and the impact it has made on her life.

  • Bita Badakhshan
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    Watch an interview with Dr. Bita Badakhshan, a seasoned practitioner in primary family medicine with over 12 years of experience in integrative oncology and functional medicine.

    In this video, Dr. Bita shares her experience with RGCC’s transformative liquid biopsy testing. She highlights the unparalleled precision and detail offered by RGCC's advanced methodologies over other laboratories.

    Dr. Bita emphasizes the unmatched sensitivity of RGCC's testing, which delves deep into analyzing stem cells, cancer cells, and a comprehensive array of markers crucial for personalized cancer care.

    Since 2012, Dr. Beta has trusted RGCC for blood testing on patients, particularly focusing on circulating tumor cell analysis and using RGCC’s Oncocount and Oncotrace tests along with the Onconomics Plus assessments.

    Through RGCC's innovative tests and therapies, Dr. Bita has been able to make informed decisions sparing many patients from unnecessary chemotherapy and radiation post-tumor removal surgeries.

    Podcast video cover
    Podcast - Innovation in Early Cancer Detection

    Join host Sam Tejada for an essential conversation about cancer innovation and breakthroughs on this episode of A Healthy Point of View, including a close look at advances in early cancer detection - as early as stage ZERO.

    Tejada sits down with two leading medical experts: Dr. Christopher Davis, an interventional cardiologist and CMO of Liquivida, and Dr. Ioannis Papasotiriou, MD, PhD, SCym, the founder of RGCC.

    Together, they tackle one of medicine's most complex challenges, sharing cutting-edge insights and breakthrough approaches that could transform how we understand and address cancer care.

Videos

Explore our curated collection of videos, providing an in-depth look at our innovative solutions and groundbreaking research.

  • Dr Clayton Bell video cover
    Dr. Clayton Bell, MD | Gathering 2023 Interview

    In this insightful interview from the 2023 RGCC Gathering, Dr. Clayton Bell shares his journey of integrating RGCC technologies into his practice in the U.S.

    With a background in Functional, Environmental, and Integrative Medicine, Dr. Bell reveals how he uses RGCC’s cutting-edge cancer diagnostics and therapies to support his patients’ healing. Watch the full video to learn more.

  • Helena Pohlmann video cover
    Helena Pohlmann | Gathering 2023 Interview

    Helena Pöhlmann who specializes in holistic medicine shares how she utilizes RGCC products in her clinic to best support her patients. Watch the video to learn about her experience at the 2023 RGCC Gathering in Switzerland.

  • Jenny Hrbacek, RN | About RGCC Testing

    Cancer survivor and RGCC Practitioner, Jenny Hrbaceck, discusses RGCC testing and the impact it has made on her life.

  • Bita Badakhshan
    Bita Badakhshan - RGCC Gathering 2023 Interview

    Watch an interview with Dr. Bita Badakhshan, a seasoned practitioner in primary family medicine with over 12 years of experience in integrative oncology and functional medicine.

    In this video, Dr. Bita shares her experience with RGCC’s transformative liquid biopsy testing. She highlights the unparalleled precision and detail offered by RGCC's advanced methodologies over other laboratories.

    Dr. Bita emphasizes the unmatched sensitivity of RGCC's testing, which delves deep into analyzing stem cells, cancer cells, and a comprehensive array of markers crucial for personalized cancer care.

    Since 2012, Dr. Beta has trusted RGCC for blood testing on patients, particularly focusing on circulating tumor cell analysis and using RGCC’s OncoCount and OncoTrace tests along with the Onconomics Plus assessments.

    Through RGCC's innovative tests and therapies, Dr. Bita has been able to make informed decisions sparing many patients from unnecessary chemotherapy and radiation post-tumor removal surgeries.

    Read more about our therapies on our website: https://rgcc-international.com/rgcc-therapies/

    RGCC was launched in 2004 by genetics pioneer Dr. Ioannis Papasotiriou who believes that the key to effectively treating cancer lies in personalized medicine using the information in a patient’s genes.

    Individualized treatment for cancer is the focus behind RGCC’s testing protocols and advanced therapy options. Our slate of tests analyzes the state of a person’s cancer by looking at the cellular and genetic makeup of each patient. Our test results give you information that acts as a blueprint for what treatment protocols are likely to show the most efficacy for your specific biology.

    Learn more about RGCC at
    https://rgcc-international.com/

    Follow us on social media to find out the latest news and updates from our experts.

    Facebook: https://www.facebook.com/profile.php?id=61554630098937

    Instagram: https://www.instagram.com/rgcc_north_america/

    LinkedIn: https://www.linkedin.com/company/r-g-c-c-international-gmbh/

  • Podcast video cover
    Podcast - Innovation in Early Cancer Detection

    Join host Sam Tejada for an essential conversation about cancer innovation and breakthroughs on this episode of A Healthy Point of View, including a close look at advances in early cancer detection - as early as stage ZERO.

    Tejada sits down with two leading medical experts: Dr. Christopher Davis, an interventional cardiologist and CMO of Liquivida, and Dr. Ioannis Papasotiriou, MD, PhD, SCym, the founder of RGCC.

    Together, they tackle one of medicine's most complex challenges, sharing cutting-edge insights and breakthrough approaches that could transform how we understand and address cancer care.

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RGCC is not liable for any third-party comments or claims regarding our products. For accurate and up-to-date information about our offerings, please refer to our official website: rgcc-international.com
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Accreditations
IAS Accreditation
Testing Laboratory
View TL-836 Certificate
EN ISO 22000: 2018
No: 20101200002689
View Certificate
IAS Accreditation
Medical Laboratory
View ML-103 Certificate
ISO 22000: 2018
No: 20101200002689
View Certificate
ISO 45001: 2018
No: 20152220006395
View CertificatePolicy
ISO 22716: 2007
No: 20019220006394
View Certificate
CLIA ID Number
99D2283882
View Certificate
College of American Pathologists 
Certificate of Accreditation
CAP#: 9239089 
CLIA#: 99D2283882 
View Certificate
Certificate of GMP Compliance
No. 512863-102689104
View Certificate
Accreditation Certificate of Foreign Cell Processor - Japanese Government
View Certificate
EOF GMP COSMETICS – SUPPLEMENTS
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