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Our tests | CTC Tests

OncoTrail test

The OncoTrail test provides crucial information on the presence of circulating tumor cells (CTCs) and their concentration in patients who have a confirmed diagnosis of specific types of cancer. 

The OncoTrail test analyzes the markers for very specific types of cancer, including:

  • Breast cancer
  • Colon cancer
  • GI cancer
  • Melanoma cancer
  • Lung cancer
  • Sarcoma cancer
  • Prostate cancer

For instance, the breast cancer OncoTrail test will only include markers for breast cancer.

We do not use OncoTrail as a primary diagnostic test to confirm a cancer diagnosis. For this, we recommend the OncoTrace test, which is a more comprehensive tool to discover all primary and secondary cancer types.

However, once the cancer type has been identified, the OncoTrail test provides essential information on the effectiveness of current cancer treatments focused on your type of cancer. Follow-up tests can also be used to monitor your health and assess the risk of recurrence.


Purpose of the OncoTrail test

Let’s look at the three types of information returned by the OncoTrail test and their purpose in developing an individualized treatment plan for you.

CTC count

The CTC count gives a reading of the presence of cancer cells in your bloodstream. The CTC count helps your care practitioners assess the effectiveness of the established treatment protocols. And you can see a direct correlation between the CTC count and the growth or decline in cancer cells in your body.

Phenotype markers

The OncoTrail test also provides information about phenotype markers for your cancer cells. These are tissue markers that identify the tissue where the tumor cells originate.

In this case, a marker is any mutation that distinguishes (or marks) some part of the DNA or genome. Phenotype biomarkers are defined as the expression, localization, dynamics, and modification state of DNA, RNA, and proteins connected to the cancerous tumor. 

Phenotypic biomarkers are useful for:

  • Screening - Identifying at-risk individuals
  • Diagnosis - Confirming the presence of cancer
  • Staging and prognosis - Risk stratifying and predicting disease outcome
  • Companion diagnostics - Predicting the cell's level of resistance and potential response to treatments
  • Monitoring disease - Evaluating therapeutic response and recurrence
Stemness markers

The third type of information recorded by the OncoTrail test is data on the stem cell markers for your cancer, called the stemness markers. The stemness markers provide information on the behavior and activity level of cancer cells in the bloodstream. 

If the stemness markers are in an active state (or “On” position), it shows high levels of activity of cancer cells, indicating the cancer can proliferate, metastasize, or recur.

How OncoTrail results are useful

OncoTrail results are used for comprehensive monitoring of the effectiveness of your cancer treatment plan. If your cancer has gone into remission, the OncoTrail can be an extremely effective instrument for early detection of recurrence. 

Conventional monitoring treatment options can detect recurring cancer only once the tumor has grown large enough to be visible on imaging tests. 

The goal of cancer treatment is to reduce the number of CTCs in the bloodstream. Once this is achieved, you may think that cancer has been eliminated. But this is only half the picture. 

The additional information about the activity of the stemness markers recorded in the OncoTrail results adds crucial information about your cancer prognosis.

  • For early cancer, active stemness markers can mean that cancer will likely proliferate or grow.
  • For existing cancer, active stemness markers can mean cancer may metastasize.
  • For cancer in remission, active stemness markers can mean there is a propensity for cancer to recur.

Therefore, the activity levels of the stemness markers give you a true indication of whether treatment needs to continue - even when the CTC count has reached a desired low number.

This means treatment protocols can start early instead of waiting for any further worsening of the situation.

As you progress with your treatment, the package of information provided by the OncoTrail test can be a powerful tool to assess how well things are going with your cancer treatment.

Once the cancer is in full remission and the first 2-3 follow-up tests show the condition as stable, the CTC tests can be taken every 6 months as part of your monitoring protocols.

Regular monitoring is vital for the early detection of recurrence and living a cancer-free life.

Our testing protocols empower you and your care team with information that tells you about what is happening with your cancer at all times.

What to expect with the OncoTrail test

The OncoTrail test is designed as a follow-up and monitoring test for patients who are undergoing cancer treatment or have had cancer in the past and may be worried about the disease returning.

Our accredited practitioners can use OncoTrail results to assess the effectiveness of cancer treatment and evaluate the likelihood of cancer returning.

The OncoTrail test is performed using a liquid biopsy. Patients provide us with their blood samples, and no surgery or tissue biopsy is needed. The sample is then shipped to our laboratory in Greece for analysis.

Please note that if a patient is undergoing cancer treatment, we recommend waiting 7 to 21 days or more after chemotherapy to take the test.

All our accredited practitioners and clinicians understand our shipping instructions and ensure the sample arrives in perfect condition.

Price in Euros: EUR 775

* Prices in $USD vary slightly based on the exchange rate on the day the test is ordered.
** These prices do not include in-office fees such as consultation, blood draws, IV administration, etc.

View an OncoTrail result sample

To know what to expect from the test results, view a sample OncoTrail test result. Click on the link for the type of cancer to see the sample for it.

Accessing the results

Your sample will be processed at our state-of-the-art laboratory in Greece. Once the test is completed, we will provide a detailed breakdown of our findings. The results are sent to your accredited practitioner who downloads the results and sets up an appointment with you to go over the results.

We recommend that you also discuss the results with your cancer care team and work together to develop a personalized treatment plan based on our findings.

Access cutting-edge cancer care tools with our CTC tests

Our scientists use world-leading technology, equipment, and innovative techniques to develop a range of cancer screening and monitoring tests. Our tests help cancer patients and their healthcare professionals get a comprehensive but personalized view of each patient’s genetics, physiology, and immune profiles.

We believe this level of detail is crucial in developing an individualized care plan for every patient struggling with cancer. We aim to provide a unique insight into every patient’s cancer biology to empower them about what treatment options are ideal for bringing them success in their cancer journey!

Reach out to us to start your journey to empowering information today by contacting us online.

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